|
New member Username: HannahcoleShirley, New York United states Post Number: 1 Registered: Feb-25 | Patient-derived xenograft (PDX) models have become an indispensable tool in cancer research, largely owing to their ability to accurately re-create the biology of human tumors. PDX models, by implanting human tumor tissue in immune-deficient mice, produce tumors very similar to the original tumors, both in histopathology, genetics, and therapeutic response. An important breakthrough in the PDX model is the re-establishment of human immune system, making it possible to study similar immune responses in humans, especially in the development of immunotherapies. https://www.creative-bioarray.com/pdx-based-drug-screening.htm |