Just from raw drivers available? Depends on what I'd want, but here's my short list:
Forward Clarity & Detail: SEAS Excel/Lotus drivers combined with the Focal TN51 tweeter, likely a 3 way front stage.
Transparency & Natural sound: Dynaudio, DLS, or Morel drivers all around
Dynamics: 2 Adire Audio Extremis midbass drivers (2 per side, 4 total) combined with either Image Dynamics or USD Audio waveguide horns. Titanium supertweeters in pillars, not sure what brand I'd choose. Another option would be a good 8" or 10" that could play accurately to around 600hz or so.